Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm

Abdominal aortic aneurysms are serious and difficult to detect, conditions can be deadly if they rupture. In this study, the heat transfer and flow physics of Abdominal Aortic Aneurysm (AAA) were discussed and associated with cardiac cycle to illustrate the cardiac thermal pulse (CTP) of AAA. A CTP...

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Main Authors: Ng, Eddie Yin Kwee, Looi, Leonard Jun Cong
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/10356/168548
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-1685482023-06-10T16:47:48Z Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm Ng, Eddie Yin Kwee Looi, Leonard Jun Cong School of Mechanical and Aerospace Engineering Engineering::Mechanical engineering Unsteady Blood Flow Transient Bioheat Transfer Abdominal aortic aneurysms are serious and difficult to detect, conditions can be deadly if they rupture. In this study, the heat transfer and flow physics of Abdominal Aortic Aneurysm (AAA) were discussed and associated with cardiac cycle to illustrate the cardiac thermal pulse (CTP) of AAA. A CTP and infrared thermography (IRT) evaluation-based on AAA and abdomen skin surface detection method was proposed, respectively. Infrared thermography (IRT) is a promising imaging technique that may detect AAA quicker and cheaper than other imaging techniques (as biomarker). From CFD rigid-wall and FSI Analysis, the transient bioheat transfer effect resulted in a distinct thermal signature (circular thermal elevation) on the temperature profile of midriff skin surface, at both regular body temperature and supine position, under normal clinical temperature. However, it is important to note that thermography is not a perfect technology, and it does have some limitations, such as lack of clinical trials. There is still work to be done to improve this imaging technique and make it a more viable and accurate method for detecting abdominal aortic aneurysms. However, thermography is currently one of the most convenient technologies in this field, and it has the potential to detect abdominal aortic aneurysms earlier than other techniques. CTP, on the other hand, was used to examine the thermal physics of AAA. In CFD rigid-wall Analysis, AAA had a CTP that only responded to systolic phase at regular body temperature. In contrast, a healthy abdominal aorta displayed a CTP that responded to the full cardiac cycle, including diastolic phase at all simulated cases. Besides, the findings from FSI Analysis suggest the influence of numerical simulation techniques on the prediction of thermal physics behaviours of AAA and abdominal skin surface. Lastly, this study correlated the relationship between natural convective heat transfer coefficient with AAA and provided reference for potential clinical diagnostic using IRT in clinical implications. Published version 2023-06-05T06:32:21Z 2023-06-05T06:32:21Z 2022 Journal Article Ng, E. Y. K. & Looi, L. J. C. (2022). Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm. Mathematical Biosciences and Engineering, 19(10), 10213-10251. https://dx.doi.org/10.3934/mbe.2022479 1547-1063 https://hdl.handle.net/10356/168548 10.3934/mbe.2022479 36031992 2-s2.0-85135067770 10 19 10213 10251 en Mathematical Biosciences and Engineering © 2022 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0). application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Mechanical engineering
Unsteady Blood Flow
Transient Bioheat Transfer
spellingShingle Engineering::Mechanical engineering
Unsteady Blood Flow
Transient Bioheat Transfer
Ng, Eddie Yin Kwee
Looi, Leonard Jun Cong
Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
description Abdominal aortic aneurysms are serious and difficult to detect, conditions can be deadly if they rupture. In this study, the heat transfer and flow physics of Abdominal Aortic Aneurysm (AAA) were discussed and associated with cardiac cycle to illustrate the cardiac thermal pulse (CTP) of AAA. A CTP and infrared thermography (IRT) evaluation-based on AAA and abdomen skin surface detection method was proposed, respectively. Infrared thermography (IRT) is a promising imaging technique that may detect AAA quicker and cheaper than other imaging techniques (as biomarker). From CFD rigid-wall and FSI Analysis, the transient bioheat transfer effect resulted in a distinct thermal signature (circular thermal elevation) on the temperature profile of midriff skin surface, at both regular body temperature and supine position, under normal clinical temperature. However, it is important to note that thermography is not a perfect technology, and it does have some limitations, such as lack of clinical trials. There is still work to be done to improve this imaging technique and make it a more viable and accurate method for detecting abdominal aortic aneurysms. However, thermography is currently one of the most convenient technologies in this field, and it has the potential to detect abdominal aortic aneurysms earlier than other techniques. CTP, on the other hand, was used to examine the thermal physics of AAA. In CFD rigid-wall Analysis, AAA had a CTP that only responded to systolic phase at regular body temperature. In contrast, a healthy abdominal aorta displayed a CTP that responded to the full cardiac cycle, including diastolic phase at all simulated cases. Besides, the findings from FSI Analysis suggest the influence of numerical simulation techniques on the prediction of thermal physics behaviours of AAA and abdominal skin surface. Lastly, this study correlated the relationship between natural convective heat transfer coefficient with AAA and provided reference for potential clinical diagnostic using IRT in clinical implications.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Ng, Eddie Yin Kwee
Looi, Leonard Jun Cong
format Article
author Ng, Eddie Yin Kwee
Looi, Leonard Jun Cong
author_sort Ng, Eddie Yin Kwee
title Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
title_short Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
title_full Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
title_fullStr Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
title_full_unstemmed Numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
title_sort numerical analysis of biothermal-fluids and cardiac thermal pulse of abdominal aortic aneurysm
publishDate 2023
url https://hdl.handle.net/10356/168548
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