Single-cell transcriptome of wet AMD patient-derived endothelial cells in angiogenic sprouting

• المؤلفون الرئيسيون: Yeo, Natalie Jia Ying, Wazny, Vanessa, Nhi Le Uyen Nguyen, Ng, Chun Yi, Wu, Kan Xing, Fan, Qiao, Cheung, Gemmy Chui Ming, Cheung, Christine
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Medicine; Age-Related Macular Degeneration; Blood Outgrowth Endothelial Cells
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/168553
• المؤسسة: Nanyang Technological University

Age-related macular degeneration (AMD) is a global leading cause of visual impairment in older populations. 'Wet' AMD, the most common subtype of this disease, occurs when pathological angiogenesis infiltrates the subretinal space (choroidal neovascularization), causing hemorrhage and reti...