Redox dyshomeostasis modulation of the tumor intracellular environment through a metabolic intervention strategy for enhanced photodynamic therapy

• Main Authors: Yang, Zuo, Qiao, Chaoqiang, Jia, Qian, Chen, Zhuang, Wang, Xiaofei, Liu, Xuelan, Zhang, Ruili, Pu, Kanyi, Wang, Zhongliang
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Chemical engineering; Photodynamic Therapy; Metal-Organic Framework
• Online Access: https://hdl.handle.net/10356/168617
• Institution: Nanyang Technological University

Rationale: Photodynamic therapy (PDT) is a clinically approved anticancer treatment with a promising therapeutic prospect, however, usually suffers from the unfavorable intracellular environment including cellular hypoxia and excessive glutathione (GSH). Comprehensive and long-term modulation of tum...