Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue

Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue

Dengue can be complicated by severe outcomes including cardiac impairment, and the lack of reliable prognostic biomarkers poses a challenge in managing febrile dengue patients. Here, we investigated the functionality of soluble suppressor of tumorigenicity (sST2) as a predictive marker of severe den...

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Main Authors: Teo, Andrew, Chia, Po Ying, Ramireddi, Gaurav Kumar, Khoo, Sebastian Kah Ming, Yeo, Tsin Wen
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Biomarkers
Humans
Online Access:https://hdl.handle.net/10356/168624
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1686242023-06-18T15:38:53Z Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue Teo, Andrew Chia, Po Ying Ramireddi, Gaurav Kumar Khoo, Sebastian Kah Ming Yeo, Tsin Wen Lee Kong Chian School of Medicine (LKCMedicine) National Centre for Infectious Diseases Tan Tock Seng Hospital Science::Medicine Biomarkers Humans Dengue can be complicated by severe outcomes including cardiac impairment, and the lack of reliable prognostic biomarkers poses a challenge in managing febrile dengue patients. Here, we investigated the functionality of soluble suppressor of tumorigenicity (sST2) as a predictive marker of severe dengue and its association in dengue-associated cardiac impairment. Nanyang Technological University National Medical Research Council (NMRC) Published version This study was funded by Clinician Scientist Award INV 15nov007 awarded to TWY and National Centre for Infectious Diseases Catalyst Grant FY202008AT awarded to AT; AT is supported by LKC Medicine Dean’s Postdoctoral Fellowship and Nanyang Technological University Research Scholarship Block; PYC was supported by NMRC Research Training Fellowship PYC (NMRC/Fellowship/0056/2018). 2023-06-12T06:41:16Z 2023-06-12T06:41:16Z 2022 Journal Article Teo, A., Chia, P. Y., Ramireddi, G. K., Khoo, S. K. M. & Yeo, T. W. (2022). Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue. PLOS Neglected Tropical Diseases, 16(10), e0010864-. https://dx.doi.org/10.1371/journal.pntd.0010864 1935-2727 https://hdl.handle.net/10356/168624 10.1371/journal.pntd.0010864 36228040 2-s2.0-85140855801 10 16 e0010864 en CSA INV 15nov007 FY202008AT NMRC/Fellowship/0056/2018 PLOS Neglected Tropical Diseases © 2022 Teo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Biomarkers
Humans
spellingShingle Science::Medicine
Biomarkers
Humans
Teo, Andrew
Chia, Po Ying
Ramireddi, Gaurav Kumar
Khoo, Sebastian Kah Ming
Yeo, Tsin Wen
Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue
description Dengue can be complicated by severe outcomes including cardiac impairment, and the lack of reliable prognostic biomarkers poses a challenge in managing febrile dengue patients. Here, we investigated the functionality of soluble suppressor of tumorigenicity (sST2) as a predictive marker of severe dengue and its association in dengue-associated cardiac impairment.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Teo, Andrew
Chia, Po Ying
Ramireddi, Gaurav Kumar
Khoo, Sebastian Kah Ming
Yeo, Tsin Wen
format Article
author Teo, Andrew
Chia, Po Ying
Ramireddi, Gaurav Kumar
Khoo, Sebastian Kah Ming
Yeo, Tsin Wen
author_sort Teo, Andrew
title Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue
title_short Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue
title_full Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue
title_fullStr Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue
title_full_unstemmed Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue
title_sort clinical and prognostic relevance of sst2 in adults with dengue-associated cardiac impairment and severe dengue
publishDate 2023
url https://hdl.handle.net/10356/168624
_version_ 1772826976155860992

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