Formulation strategies to improve the stability and handling of oral solid dosage forms of highly hygroscopic pharmaceuticals and nutraceuticals

• Main Authors: Ng, Liu Han, Ling, Jordy Kim Ung, Hadinoto, Kunn
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; Hygroscopic Pharmaceuticals; Pharmaceutical Coating
• Online Access: https://hdl.handle.net/10356/168630
• Institution: Nanyang Technological University

Highly hygroscopic pharmaceutical and nutraceutical solids are prone to significant changes in their physicochemical properties due to chemical degradation and/or solid-state transition, resulting in adverse effects on their therapeutic performances and shelf life. Moisture absorption also leads to...