Perspectives for better batch effect correction in mass-spectrometry-based proteomics

• Main Authors: Phua, Ser-Xian, Lim, Kai-Peng, Goh, Wilson Wen Bin
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Proteomics; Batch Effects
• Online Access: https://hdl.handle.net/10356/168633
• Institution: Nanyang Technological University

Mass-spectrometry-based proteomics presents some unique challenges for batch effect correction. Batch effects are technical sources of variation, can confound analysis and usually non-biological in nature. As proteomic analysis involves several stages of data transformation from spectra to protein,...