Developing a zebrafish model of bisphosphonate induced osteonecrosis of jaw to define cellular and molecular mechanisms

Bisphosphonates are critical drugs of the orthopaedic clinic, which act by inhibiting osteoclast resorptive activity and thus promote bone density. They are commonly used for treating Osteogenesis Imperfecta (OI), Paget’s disease, osteoporosis, and bone metastasis. In particular, the global rise in...

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Bibliographic Details
Main Author: Ethiraj, Lalith Prabha
Other Authors: Tom James Carney
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2023
Subjects:
Online Access:https://hdl.handle.net/10356/168636
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Institution: Nanyang Technological University
Language: English