Photonic bandgap fiber microlaser with dual-band emission for integrated optical tagging and sensing

• Main Authors: Wang, Yanqiong, Gong, Chaoyang, Yang, Xi, Zhu, Tao, Zhang, Ke, Rao, Yun-Jiang, Wei, Lei, Gong, Yuan
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Electrical and electronic engineering; Disease Screening; Encoding
• Online Access: https://hdl.handle.net/10356/168883
• Institution: Nanyang Technological University

Lasers are emerging as novel photonic tags for single-cell labeling, anticounterfeiting, and encryption technology due to their narrow linewidth, high spectral multiplexing capacity, and superior stimuli-responsiveness. These laser-encoded photonic tags mostly distinguish the heterogeneity but do not yet provide both tagging and sensing of biosamples, which is highly desirable for disease screening. Here, a photonic bandgap (PBG) fiber microlaser that works as a 2D tag and an immunosensor is developed. The tubular PBG structure allows strong light–matter interaction and supports dual-band lasing in the same optical fiber, enabling massive biosample tagging and sensitive biodetection. By encoding the random resonant peaks in the short-wave band and multiplexing in the spatial domain, a 2D laser tag is generated with a large encoding capacity (>28500). Immunosensing of microalbumin is realized by using the periodic resonant peaks in the long-wave band, and a limit of detection of 0.06 ng µL−1 is achieved. This work is inspiring for the development of high-performance, multifunctional integrated devices for disease screening.