Dendritic plasmonic CuPt alloys for closed-loop multimode cancer therapy with remarkably enhanced efficacy

• Main Authors: Chang, Mengyu, Wang, Man, Liu, Yuhui, Liu, Min, Kheraif, Abdulaziz A. Al, Ma, Ping'an, Zhao, Yanli, Lin, Jun
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Bioengineering; Laser Activation; Mitochondrial Respiration Inhibition
• Online Access: https://hdl.handle.net/10356/168898
• Institution: Nanyang Technological University

The outcome of laser-triggered plasmons-induced phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), is significantly limited by the hypoxic tumor microenvironment and the upregulation of heat shock proteins (HSPs) in response to heat stress. Mitochondria, the biologica...