Unraveling how cholesterol affects multivalency-induced membrane deformation of sub-100 nm lipid vesicles

• Main Authors: Park, Hyeonjin, Sut, Tun Naw, Yoon, Bo Kyeong, Zhdanov, Vladimir P., Cho, Nam-Joon, Jackman, Joshua A.
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Materials; Biomimetics; Ligands
• Online Access: https://hdl.handle.net/10356/168944
• Institution: Nanyang Technological University

Cholesterol plays a critical role in modulating the lipid membrane properties of biological and biomimetic systems and recent attention has focused on its role in the functions of sub-100 nm lipid vesicles and lipid nanoparticles. These functions often rely on multivalent ligand-receptor interaction...