Glial cells expressing visual cycle genes are vital for photoreceptor survival in the zebrafish pineal gland

• Main Authors: Elazary, Yotam, Cheow, Kathleen, Cheng, Ruey-Kuang, Ghosh, Raghumoy, Shainer, Inbal, Wexler, Yair, Crasta, Karen, Gothilf, Yoav, Jesuthasan, Suresh
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Photoreceptor; Exosome
• Online Access: https://hdl.handle.net/10356/169057
• Institution: Nanyang Technological University

Photoreceptors in the vertebrate eye are dependent on the retinal pigmented epithelium for a variety of functions including retinal re-isomerization and waste disposal. The light-sensitive pineal gland of fish, birds, and amphibians is evolutionarily related to the eye but lacks a pigmented epitheli...