Oligomer nanoparticle release from polylactic acid plastics catalysed by gut enzymes triggers acute inflammation

• Main Authors: Wang, Mengjing, Li, Qianqian, Shi, Changzhi, Lv, Jia, Xu, Youdong, Yang, Junjie, Chua, Shae Linn, Jia, Linran, Chen, Huaiwen, Liu, Qian, Huang, Changjin, Huang, Yichao, Chen, Jianmin, Fang, Mingliang
• Other Authors: School of Civil and Environmental Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Environmental engineering; Binding Energy; Biodegradable Polymers
• Online Access: https://hdl.handle.net/10356/169072
• Institution: Nanyang Technological University

The health risks of exposure to 'eco-friendly' biodegradable plastics of anthropogenic origin and their effects on the gastrointestinal tract are largely unknown. Here we demonstrate that the enzymatic hydrolysis of polylactic acid microplastics generated nanoplastic particles by competing...