Improving gene therapy

• Main Author: Wang, Eliza Lisha
• Other Authors: Klaus Erik Karjalainen
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology
• Online Access: http://hdl.handle.net/10356/16911
• Institution: Nanyang Technological University

Retroviral mediated gene therapy has progressed along with advances in biological science. Existing PT67 and Amphotropic-Phoenix retroviral packaging cell lines can be made more efficient to produce higher retroviral titers, giving rise to more efficient gene transfer. Here, an IRES-mcherry gene was...