The cytoplasmic N-terminal tail of Zika virus NS4A protein forms oligomers in the absence of detergent or lipids

• المؤلفون الرئيسيون: Surya, Wahyu, Liu, Yiting, Torres, Jaume
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Viral Nonstructural Protein; Zika Virus
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/169227
• المؤسسة: Nanyang Technological University

The non-structural (NS) NS4A protein in flaviviruses has three predicted transmembrane domains, is critical for virulence and participates in membrane morphogenesis. In Dengue virus (DENV), both hydrophylic N-terminal tail and its first transmembrane domain participate in the formation of oligomers...