Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice

• المؤلفون الرئيسيون: Kang, Xing, Ng, Siu-Kin, Liu, Changan, Lin, Yufeng, Zhou, Yunfei, Kwong, Thomas N. Y., Ni, Yunbi, Lam, Thomas Y. T., Wu, William K. K., Wei, Hong, Sung, Joseph Jao Yiu, Yu, Jun, Wong, Sunny Hei
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Medicine; Obesity; Microbiota
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/169288

Background: Obesity is a risk factor for colorectal cancer (CRC). The role of gut microbiota in mediating the cancer-promoting effect of obesity is unknown. Methods: Azoxymethane (AOM)-treated, ApcMin/+ and germ-free mice were gavaged with feces from obese individuals and control subjects respective...