NF-κB/p52 augments ETS1 binding genome-wide to promote glioma progression

• Main Authors: Sim, Nicholas, Li, Yinghui
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Glioma; ETS1 Protein
• Online Access: https://hdl.handle.net/10356/169293
• Institution: Nanyang Technological University

Gliomas are highly invasive and chemoresistant cancers, making them challenging to treat. Chronic inflammation is a key driver of glioma progression as it promotes aberrant activation of inflammatory pathways such as NF-κB signalling, which drives cancer cell invasion and angiogenesis. NF-κB factors...