Severe thrombocytopenia, thrombosis and anti-PF4 antibody after Pfizer-BioNTech COVID-19 mRNA vaccine booster-Is it vaccine-induced Immune thrombotic thrombocytopenia?

• Main Authors: Ling, Victor W. T., Fan, Eugene Bingwen, Lau, Soon Lee, Lee, Xiu Hue, Tan, Chuen Wen, Lee, Shir Ying
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Thrombocytopenia; COVID-19 Vaccine
• Online Access: https://hdl.handle.net/10356/169481
• Institution: Nanyang Technological University

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a serious and life-threatening complication occurring after adenovirus-vector COVID-19 vaccines, and is rarely reported after other vaccine types. Herein, we report a case of possible VITT after the Pfizer-BioNTech mRNA vaccine booster, wh...