Applications of deep learning to neurodevelopment in pediatric imaging: achievements and challenges

Deep learning has achieved remarkable progress, particularly in neuroimaging analysis. Deep learning applications have also been extended from adult to pediatric medical images, and thus, this paper aims to present a systematic review of this recent research. We first introduce the commonly used dee...

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Bibliographic Details
Main Authors: Hu, Mengjiao, Nardi, Cosimo, Zhang, Haihong, Ang, Kai Keng
Other Authors: School of Computer Science and Engineering
Format: Article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/10356/169518
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Institution: Nanyang Technological University
Language: English
Description
Summary:Deep learning has achieved remarkable progress, particularly in neuroimaging analysis. Deep learning applications have also been extended from adult to pediatric medical images, and thus, this paper aims to present a systematic review of this recent research. We first introduce the commonly used deep learning methods and architectures in neuroimaging, such as convolutional neural networks, auto-encoders, and generative adversarial networks. A non-exhaustive list of commonly used publicly available pediatric neuroimaging datasets and repositories are included, followed by a categorical review of recent works in pediatric MRI-based deep learning studies in the past five years. These works are categorized into recognizing neurodevelopmental disorders, identifying brain and tissue structures, estimating brain age/maturity, predicting neurodevelopment outcomes, and optimizing MRI brain imaging and analysis. Finally, we also discuss the recent achievements and challenges on these applications of deep learning to pediatric neuroimaging.