MSC-sEV treatment polarizes pro-fibrotic M2 macrophages without exacerbating liver fibrosis in NASH

• المؤلفون الرئيسيون: Zhang, Bin, Zhang, Biyan, Lai, Ruenn Chai, Sim, Wei Kian, Lam, Kong Peng, Lim, Sai Kiang
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Immunomodulation; M2 Macrophage
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/169574

Mesenchymal stem/stromal cell small extracellular vesicles (MSC-sEVs) have shown promise in treating a wide range of animal models of various human diseases, which has led to their consideration for clinical translation. However, the possibility of contraindication for MSC-sEV use is an important co...