MSC-sEV treatment polarizes pro-fibrotic M2 macrophages without exacerbating liver fibrosis in NASH

• Main Authors: Zhang, Bin, Zhang, Biyan, Lai, Ruenn Chai, Sim, Wei Kian, Lam, Kong Peng, Lim, Sai Kiang
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Science::Biological sciences; Immunomodulation; M2 Macrophage
• 在線閱讀: https://hdl.handle.net/10356/169574
• 機構: Nanyang Technological University

Mesenchymal stem/stromal cell small extracellular vesicles (MSC-sEVs) have shown promise in treating a wide range of animal models of various human diseases, which has led to their consideration for clinical translation. However, the possibility of contraindication for MSC-sEV use is an important co...