Dysfunctional autophagy, proteostasis, and mitochondria as a prelude to age-related macular degeneration

Dysfunctional autophagy, proteostasis, and mitochondria as a prelude to age-related macular degeneration

Retinal pigment epithelial (RPE) cell dysfunction is a key driving force of AMD. RPE cells form a metabolic interface between photoreceptors and choriocapillaris, performing essential functions for retinal homeostasis. Through their multiple functions, RPE cells are constantly exposed to oxidative s...

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Bibliographic Details
Main Authors: Lenin, Raji Rajesh, Koh, Yi Hui, Zhang, Zheting, Yeo, Yan Zhuang, Parikh, Bhav Harshad, Seah, Ivan, Wong, Wendy, Su, Xinyi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Mitochondrial Dysfunction
Age-Related Macular Degeneration
Online Access:https://hdl.handle.net/10356/169575
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/169575

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