Vitamin B12 ameliorates the pathological phenotypes of multiple Parkinson’s disease models by alleviating oxidative stress

• Main Authors: Wu, Yue, Zhao, Zhongting, Yang, Naidi, Xin, Chenqi, Li, Zheng, Xu, Jiajia, Ma, Bo, Lim, Kah-Leong, Li, Lin, Wu, Qiong, Yu, Changmin, Zhang, Chengwu
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Parkinson’s Disease; Vitamin B12
• Online Access: https://hdl.handle.net/10356/169579
• Institution: Nanyang Technological University

Parkinson's disease (PD) is the second most common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra of the midbrain. The etiology of PD has yet to be elucidated, and the disease remains incurable. Increasing evidence suggests that oxida...