Binding behavior between transforming-growth-factor-beta1 and its receptor reconstituted in biomimetic membranes

• Main Authors: Shin, Gounhanul, Hadinoto, Kunn, Lee, Sungmun, Park, Jin-Won
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Chemical technology; Biomimetic Membranes; Binding
• Online Access: https://hdl.handle.net/10356/169584
• Institution: Nanyang Technological University

Transforming growth factor β1 (TGF-β1) is critical to cell differentiation, proliferation, and apoptosis. It is important to understand the binding affinity between TGF-β1 and its receptors. In this study, their binding force was measured using an atomic force microscope. Significant adhesion was in...