Editing of a specific strain of escherichia coli in the mouse gut using native phages

• Main Authors: Li, Ping, Li, Zhuoya, Jia, Pei, Chen, Jingchao, Li, Yi, Liu, Guosheng, Wang, Hailei
• Other Authors: Nanyang Environment and Water Research Institute
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Microbial Editing; Gut Microbiome
• Online Access: https://hdl.handle.net/10356/169627
• Institution: Nanyang Technological University

There is a lack of methodological investigation of the in situ functions of bacterial species in microecosystems. Here, we used native phages as a microbial editing tool for eliminating Escherichia coli strain MG1655 labeled with green fluorescent protein (GFP) in the mouse gut. The virulent phages...