Multidimensional conservation analysis decodes the expression of conserved long noncoding RNAs

• Main Authors: Zhou, Qiuzhong, Jiang, Yuxi, Cai, Chaoqun, Li, Wen, Leow, Melvin Khee-Shing, Yang, Yi, Liu, Jin, Xu, Dan, Sun, Lei
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Gene Expression Regulation; Biological Evolution
• Online Access: https://hdl.handle.net/10356/169703
• Institution: Nanyang Technological University

Although long noncoding RNAs (lncRNAs) experience weaker evolutionary constraints and exhibit lower sequence conservation than coding genes, they can still conserve their features in various aspects. Here, we used multiple approaches to systemically evaluate the conservation between human and mouse...