Multidimensional conservation analysis decodes the expression of conserved long noncoding RNAs

• المؤلفون الرئيسيون: Zhou, Qiuzhong, Jiang, Yuxi, Cai, Chaoqun, Li, Wen, Leow, Melvin Khee-Shing, Yang, Yi, Liu, Jin, Xu, Dan, Sun, Lei
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Gene Expression Regulation; Biological Evolution
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/169703
• المؤسسة: Nanyang Technological University

Although long noncoding RNAs (lncRNAs) experience weaker evolutionary constraints and exhibit lower sequence conservation than coding genes, they can still conserve their features in various aspects. Here, we used multiple approaches to systemically evaluate the conservation between human and mouse...