Mechanisms of a Mycobacterium tuberculosis active peptide

• Main Authors: Rao, Komal Umashankar, Li, Ping, Welinder, Charlotte, Tenland, Erik, Gourdon, Pontus, Sturegård, Erik, Ho, James Chin Shing, Godaly, Gabriela
• Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Mycobacterium Tuberculosis; Antimicrobial Peptides
• Online Access: https://hdl.handle.net/10356/169738
• Institution: Nanyang Technological University

Multidrug-resistant tuberculosis (MDR) continues to pose a threat to public health. Previously, we identified a cationic host defense peptide with activity against Mycobacterium tuberculosis in vivo and with a bactericidal effect against MDR M. tuberculosis at therapeutic concentrations. To understa...