Modulation of mechanical properties of short bioinspired peptide materials by single amino-acid mutations

• Main Authors: Hiew, Shu Hui, Lu, Yang, Han, Hao, Gonçalves, Rui A., Alfarano, Serena Rosa, Mezzenga, Raffaele, Parikh, Atul N., Mu, Yuguang, Miserez, Ali
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Materials; Science::Biological sciences; Amino Acids; Drug Delivery
• Online Access: https://hdl.handle.net/10356/169913
• Institution: Nanyang Technological University

The occurrence of modular peptide repeats in load-bearing (structural) proteins is common in nature, with distinctive peptide sequences that often remain conserved across different phylogenetic lineages. These highly conserved peptide sequences endow specific mechanical properties to the material, s...