Role of RUNX2 in mitogen-activated protein kinase (MAPK) mediated cell proliferation of breast cancer cells.

• Main Author: Goh, Xuewei.
• Other Authors: Ta Nguyen Binh Duong
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Cytology
• Online Access: http://hdl.handle.net/10356/16992
• Institution: Nanyang Technological University

RUNX2 is a key regulator of bone development and it controls genes that contribute to cell growth regulation in osteoblast. This study investigated the role that RUNX2 play in the cell proliferation regulatory pathways of breast cancer cells. From our serum stimulation study of MDA-MB-231 cells, res...