TWEAK/Fn14 distinctly remodels the transcriptomic and epigenetic landscape in triple negative breast cancer to drive its progression

• 主要作者: Sim, Nicholas Yang-U
• 其他作者: Li Yinghui
• 格式: Thesis-Doctor of Philosophy
• 語言: English
• 出版: Nanyang Technological University 2023
• 主題: Science::Biological sciences::Genetics; Science::Biological sciences::Molecular biology
• 在線閱讀: https://hdl.handle.net/10356/169950
• 機構: Nanyang Technological University

Breast cancer is the most prevalent malignancy in women and one of the leading causes of cancer-related deaths globally. Of which, roughly 20% of cases are Triple Negative Breast Cancers (TNBC) which are highly aggressive and lack hormone receptors, rendering standard systemic therapy ineffective. C...