An updated meta-analysis on the clinical outcomes of percutaneous left atrial appendage closure versus direct oral anticoagulation in patients with atrial fibrillation

• Main Authors: Jiang, Haowen, Koh, Tian Hai, Vengkat, Vijay, Fei, Gao, Ding, Zee Pin, Ewe, See Hooi, Jappar, Ignasius, Lim, Soo Teik, Yap, Jonathan
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Anticoagulation; Atrial Fibrillation
• Online Access: https://hdl.handle.net/10356/169956
• Institution: Nanyang Technological University

The availability of direct oral anticoagulants (DOACs) with known lower bleeding risk compared with warfarin have raised questions about the role of left atrial appendage closure (LAAC). We aimed to perform a meta-analysis to compare the clinical outcomes for LAAC versus DOACs. All studies directly...