Geometry-mediated bridging drives nonadhesive stripe wound healing

• Main Authors: Xu, Hongmei, Huo, Yucheng, Zhou, Quan, Wang, Abraham Lianghao, Cai, Pingqiang, Doss, Bryant, Huang, Changjin, Hsia, K. Jimmy
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Bioengineering; Gap Closure; Collective Cell Migration
• Online Access: https://hdl.handle.net/10356/170112
• Institution: Nanyang Technological University

Wound healing through reepithelialization of gaps is of profound importance to the medical community. One critical mechanism identified by researchers for closing non-cell-adhesive gaps is the accumulation of actin cables around concave edges and the resulting purse-string constriction. However, the...