Activatable immunoprotease nanorestimulator for second near-infrared photothermal immunotherapy of cancer

• Main Authors: Xu, Mengke, Zhang, Chi, He, Shasha, Xu, Cheng, Wei, Xin, Pu, Kanyi
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Cancer Therapy; Immunoprotease Restimulation
• Online Access: https://hdl.handle.net/10356/170289
• Institution: Nanyang Technological University

Photothermal immunotherapy is a combinational cancer therapy modality, wherein the photothermal process can noninvasively ablate cancer and efficiently trigger cancer immunogenic cell death to ignite antitumor immunity. However, cancer cells can resist the cytotoxic lymphocyte-mediated antitumor eff...