Activatable semiconducting polymer pro-nanomodulators for deep-tissue sono-immunotherapy of orthotopic pancreatic cancer

• Main Authors: Li, Jingchao, Yu, Ningyue, Cui, Dong, Huang, Jiaguo, Luo, Yu, Pu, Kanyi
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Chemical engineering; Cancer Therapy; Immunotherapy
• Online Access: https://hdl.handle.net/10356/170303
• Institution: Nanyang Technological University

Immunotherapy has provided a promising modality for cancer treatment, while it often has the issues of limited response rates and potential off-target side effects in clinical practice. We herein report the construction of semiconducting polymer pro-nanomodulators (SPpMs) with ultrasound (US)-mediat...