Functional characterisation of SV2C and its variants as a Parkinson’s Disease-associated gene

• Main Authors: Chang, Chu-Hua, Chew, Elaine Guo Yan, Tandiono, Moses, Zhang, Tian, Gong, Ximing, Xia, Yun, Foo, Jia Nee
• Other Authors: Interdisciplinary Graduate School (IGS)
• Format: Conference or Workshop Item
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Parkinson’s Disease; Gene
• Online Access: https://hdl.handle.net/10356/170356; https://www.sfn.org/meetings/neuroscience-2023/sessions-and-events
• Institution: Nanyang Technological University

Parkinson’s Disease (PD) is the second most common neurodegenerative disease characterised by the loss of dopaminergic neurons in the substantia nigra pars compacta in the midbrain. Extensive effort has been devoted to identifying genetic risk factors for PD to allow for early intervention and manag...