Monitoring amyloidogenesis with a 3D deep-learning-guided biolaser imaging array

• Main Authors: Chan, Kok Ken, Shang, Linwei, Qiao, Zhen, Liao, Yikai, Kim, Munho, Chen, Yu-Cheng
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Electrical and electronic engineering; Engineering::Bioengineering; Amyloidogenesis; Biolaser
• Online Access: https://hdl.handle.net/10356/170535
• Institution: Nanyang Technological University

Amyloidogenesis is a critical hallmark for many neurodegenerative diseases and drug screening; however, identifying intermediate states of protein aggregates at an earlier stage remains challenging. Herein, we developed a peptide-encapsulated droplet microlaser to monitor the amyloidogenesis process...