Synergistic antibacterial action of lignin-squaraine hybrid photodynamic therapy: advancing towards effective treatment of antibiotic-resistant bacteria

• Main Authors: Ferdinandus, Joo, Chaemin, Kai, Dan, Lee, Ken Chi-Lik
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Materials; Antibiotics; Bacteria
• Online Access: https://hdl.handle.net/10356/170591
• Institution: Nanyang Technological University

Antibacterial photodynamic therapy (aPDT) is emerging as an effective means of treating pathogenic bacteria, especially in light of the challenges posed by antibiotic resistance. SQR29, an organophotosensitizer, was encapsulated in a poly(lignin/PEG/PPG urethane) hydrogel to enable targeted treatmen...