Group-shrinkage feature selection with a spatial network for mining DNA methylation data

• Main Authors: Tang, Xinlu, Mo, Zhanfeng, Chang, Cheng, Qian, Xiaohua
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Computer science and engineering; DNA Methylation; Feature Selection
• Online Access: https://hdl.handle.net/10356/170639
• Institution: Nanyang Technological University

Identifying disease-related biomarkers from high-dimensional DNA methylation data helps in reducing early screening costs and inferring pathogenesis mechanisms. Good discovery results have been achieved through spatial correlation methods of methylation sites, group-based regularization, and network...