Neural cell membrane-coated DNA nanogels as a potential target-specific drug delivery tool for the central nervous system

• Main Authors: Lin, Po Hen, Huang, Chongquan, Hu, Yuwei, Ramanujam, Vaibavi Srirangam, Lee, Ee-Soo, Singh, Ruby, Milbreta, Ulla, Cheung, Christine, Ying, Jackie Y., Chew, Sing Yian
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Bioengineering; Engineering::Nanotechnology; Engineering::Nuclear engineering; Engineering::Materials::Biomaterials; Neural Cell Membrane Coating; Nanogel; RNA Delivery
• Online Access: https://hdl.handle.net/10356/170898
• Institution: Nanyang Technological University

A major bottleneck in drug/gene delivery to enhance tissue regeneration after injuries is to achieve targeted delivery to the cells of interest. Unfortunately, we have not been able to attain effective targeted drug delivery in tissues due to the lack of efficient delivery platforms. Since specific...