Regulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites

• Main Authors: Naito, Tomoki, Yang, Haoning, Koh, Dylan Hong Zheng, Mahajan, Divyanshu, Lu, Lei, Saheki, Yasunori
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Golgi Complex; Mitochondrial Membrane
• Online Access: https://hdl.handle.net/10356/170929
• Institution: Nanyang Technological University

Abnormal distribution of cellular cholesterol is associated with numerous diseases, including cardiovascular and neurodegenerative diseases. Regulated transport of cholesterol is critical for maintaining its proper distribution in the cell, yet the underlying mechanisms remain unclear. Here, we show...