Prediction of G4 formation in live cells with epigenetic data: a deep learning approach
G-quadruplexes (G4s) are secondary structures abundant in DNA that may play regulatory roles in cells. Despite the ubiquity of the putative G-quadruplex-forming sequences (PQS) in the human genome, only a small fraction forms G4 structures in cells. Folded G4, histone methylation and chromatin acces...
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| Main Authors: | , |
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| 格式: | Article |
| 語言: | English |
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2023
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| 在線閱讀: | https://hdl.handle.net/10356/170987 |
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| 機構: | Nanyang Technological University |
| 語言: | English |