Potential impact of various surface ligands on the cellular uptake and biodistribution characteristics of red, green, and blue emitting Cu nanoclusters

Potential impact of various surface ligands on the cellular uptake and biodistribution characteristics of red, green, and blue emitting Cu nanoclusters

Surface functionalization has a prominent influence on tuning/manipulating the physicochemical properties of nanometer scaled materials. Ultrasmall sized nanoclusters with very few atoms have received enormous attention due to their bright fluorescence, biocompatibility, lower toxicity, good colloid...

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Bibliographic Details
Main Authors: Busi, Kumar Babu, Palanivel, Mathangi, Jyothi, Kotha, Fong, Zoey Lai Guan, Zahid, Syed, Ghosh, Krishna Kanta, Agrawalla, Bikram Keshari, Gulyás, Balázs, Halkarni, Surfarazhussain S., Thondamal, Manjunatha, Padmanabhan, Parasuraman, Chakrabortty, Sabyasachi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Cellular Uptake
Cu Nanoclusters
Online Access:https://hdl.handle.net/10356/171020
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Institution: Nanyang Technological University
Language: English
Description
Summary:Surface functionalization has a prominent influence on tuning/manipulating the physicochemical properties of nanometer scaled materials. Ultrasmall sized nanoclusters with very few atoms have received enormous attention due to their bright fluorescence, biocompatibility, lower toxicity, good colloidal stability and strong photostability. These properties make them suitable for diagnostic applications. In this work, we intend to study the effect of surface functional ligands on their biodistribution both in vitro and in vivo organelle systems for bioimaging applications.

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