Different mechanisms of synapsin-induced vesicle clustering at inhibitory and excitatory synapses

Different mechanisms of synapsin-induced vesicle clustering at inhibitory and excitatory synapses

Synapsins cluster synaptic vesicles (SVs) to provide a reserve pool (RP) of SVs that maintains synaptic transmission during sustained activity. However, it is unclear how synapsins cluster SVs. Here we show that either liquid-liquid phase separation (LLPS) or tetramerization-dependent cross-linking...

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Bibliographic Details
Main Authors: Song, Sang-Ho, Augustine, George James
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Neuroscience
Liquid-Liquid Phase Separation
Synapsins
Synaptic Vesicle Trafficking
Oligomerization
Online Access:https://hdl.handle.net/10356/171043
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/171043

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