Genome instability is associated with ethnic differences between Asians and Europeans in hepatocellular carcinoma

• Main Authors: Kaya, Neslihan Arife, Chen, Jianbin, Lai, Hannah, Yang, Hechuan, Ma, Liang, Liu, Xiaodong, Alvarez, Jacob Santiago, Liu, Jin, Hillmer, Axel M., Tai, David, Sheng, Joe Yeong Poh, Hu, Zheng, Chan, Yun Shen, Chow, Pierce K. H., Mu, Yuguang, Wuestefeld, Torsten, Zhai, Weiwei
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Copy-number; Intratumor Heterogeneity
• Online Access: https://hdl.handle.net/10356/171104
• Institution: Nanyang Technological University

Hepatocellular carcinoma (HCC) is one of the deadliest cancer types with diverse etiological factors across the world. Although large scale genomic studies have been conducted in different countries, integrative analysis of HCC genomes and ethnic comparison across cohorts are lacking. Methods: We fi...