Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort
Allergic sensitization is linked to allergy development, with early sensitization often associated with worse outcomes. We aimed to identify if distinct allergic sensitization trajectories existed within a diverse and multi-ethnic Asian cohort.
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2023
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sg-ntu-dr.10356-1711162023-10-15T15:38:19Z Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort Lau, Hui Xing Chen, Zhaojin Chan, Yiong Huak Tham, Elizabeth Huiwen Goh, Anne Eng Neo Van Bever, Hugo Teoh, Oon Hoe Karnani, Neerja Gluckman, Peter D. Tan, Kok Hian Yap, Fabian Godfrey, Keith M. Eriksson, Johan G. Chong, Yap Seng Lee, Bee Wah Shek, Lynette Pei-Chi Loo, Evelyn Xiu Ling Lee Kong Chian School of Medicine (LKCMedicine) KK Women’s and Children’s Hospital Duke-NUS Medical School Science::Medicine Allergic Sensitization Trajectories Latent Class Analysis Allergic sensitization is linked to allergy development, with early sensitization often associated with worse outcomes. We aimed to identify if distinct allergic sensitization trajectories existed within a diverse and multi-ethnic Asian cohort. Agency for Science, Technology and Research (A*STAR) National Medical Research Council (NMRC) National Research Foundation (NRF) Published version This research is supported by the Singapore National Research Foundation under its Translational and Clinical Research (TCR) Flagship Programme and administered by the Singapore Ministry of Health's National Medical Research Council (NMRC), Singapore - NMRC/TCR/004-NUS/2008; NMRC/TCR/012-NUHS/2014. Additional funding is provided by the Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore. EH Tham is supported by the National Medical Research Council (NMRC) Transition Award grant [MOH-TA18nov-003] from NMRC, Singapore. Godfrey KM is supported by the UK Medical Research Council (MC_UU_12011/4), the National Institute for Health Research (NIHR Senior Investigator (NF-SI-0515-10042) and NIHR Southampton Biomedical Research Centre (IS-BRC-1215-20004)), the European Union (Erasmus + Programme ImpENSA 598488-EPP-1-2018-1-DE-EPPKA2-CBHE-JP) and the British Heart Foundation (RG/15/17/3174, SP/F/21/150013). 2023-10-13T07:47:52Z 2023-10-13T07:47:52Z 2022 Journal Article Lau, H. X., Chen, Z., Chan, Y. H., Tham, E. H., Goh, A. E. N., Van Bever, H., Teoh, O. H., Karnani, N., Gluckman, P. D., Tan, K. H., Yap, F., Godfrey, K. M., Eriksson, J. G., Chong, Y. S., Lee, B. W., Shek, L. P. & Loo, E. X. L. (2022). Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort. World Allergy Organization Journal, 15(7), 100667-. https://dx.doi.org/10.1016/j.waojou.2022.100667 1939-4551 https://hdl.handle.net/10356/171116 10.1016/j.waojou.2022.100667 35891673 2-s2.0-85134193716 7 15 100667 en NMRC/TCR/004-NUS/2008 NMRC/TCR/012-NUHS/2014 MOH-TA18nov-003 World Allergy Organization Journal © 2022 The Authors. Published by Elsevier Inc. on behalf of World Allergy Organization. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf |
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Singapore Singapore |
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| language |
English |
| topic |
Science::Medicine Allergic Sensitization Trajectories Latent Class Analysis |
| spellingShingle |
Science::Medicine Allergic Sensitization Trajectories Latent Class Analysis Lau, Hui Xing Chen, Zhaojin Chan, Yiong Huak Tham, Elizabeth Huiwen Goh, Anne Eng Neo Van Bever, Hugo Teoh, Oon Hoe Karnani, Neerja Gluckman, Peter D. Tan, Kok Hian Yap, Fabian Godfrey, Keith M. Eriksson, Johan G. Chong, Yap Seng Lee, Bee Wah Shek, Lynette Pei-Chi Loo, Evelyn Xiu Ling Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort |
| description |
Allergic sensitization is linked to allergy development, with early sensitization often associated with worse outcomes. We aimed to identify if distinct allergic sensitization trajectories existed within a diverse and multi-ethnic Asian cohort. |
| author2 |
Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet |
Lee Kong Chian School of Medicine (LKCMedicine) Lau, Hui Xing Chen, Zhaojin Chan, Yiong Huak Tham, Elizabeth Huiwen Goh, Anne Eng Neo Van Bever, Hugo Teoh, Oon Hoe Karnani, Neerja Gluckman, Peter D. Tan, Kok Hian Yap, Fabian Godfrey, Keith M. Eriksson, Johan G. Chong, Yap Seng Lee, Bee Wah Shek, Lynette Pei-Chi Loo, Evelyn Xiu Ling |
| format |
Article |
| author |
Lau, Hui Xing Chen, Zhaojin Chan, Yiong Huak Tham, Elizabeth Huiwen Goh, Anne Eng Neo Van Bever, Hugo Teoh, Oon Hoe Karnani, Neerja Gluckman, Peter D. Tan, Kok Hian Yap, Fabian Godfrey, Keith M. Eriksson, Johan G. Chong, Yap Seng Lee, Bee Wah Shek, Lynette Pei-Chi Loo, Evelyn Xiu Ling |
| author_sort |
Lau, Hui Xing |
| title |
Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort |
| title_short |
Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort |
| title_full |
Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort |
| title_fullStr |
Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort |
| title_full_unstemmed |
Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort |
| title_sort |
allergic sensitization trajectories to age 8 years in the singapore gusto cohort |
| publishDate |
2023 |
| url |
https://hdl.handle.net/10356/171116 |
| _version_ |
1781793758656856064 |