Towards next-generation sequencing for HIV-1 drug resistance testing in a clinical setting

• Main Authors: Teo, Calesta Hui Yi, Nurul Hannah Binte Norhisham, Lee, Ogestelli Fabia, Png, Siyu, Chai, Chean Nee, Yan, Gabriel, Tang, Julian Wei-Tze, Lee, Chun Kiat
• 其他作者: School of Social Sciences
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Science::Medicine; Population Sequencing; Sanger
• 在線閱讀: https://hdl.handle.net/10356/171161
• 機構: Nanyang Technological University

The HIV genotypic resistance test (GRT) is a standard of care for the clinical management of HIV/AIDS patients. In recent decades, population or Sanger sequencing has been the foundation for drug resistance monitoring in clinical settings. However, the advent of high-throughput or next-generation se...