Large-scale whole-genome sequencing of three diverse Asian populations in Singapore

• Main Authors: Wu, Degang, Dou, Jinzhuang, Chai, Xiaoran, Bellis, Claire, Wilm, Andreas, Shih, Chih Chuan, Soon, Wendy Wei Jia, Bertin, Nicolas, Lin, Clarabelle Bitong, Khor, Chiea Chuen, DeGiorgio, Michael, Cheng, Shanshan, Bao, Li, Karnani, Neerja, Hwang, William Ying Khee, Davila, Sonia, Tan, Patrick, Shabbir, Asim, Moh, Angela, Tan, Eng-King, Foo, Jia Nee, Goh, Liuh Ling, Leong, Khai Pang, Foo, Roger Sik Yin, Lam, Carolyn Su Ping, Richards, Arthur Mark, Cheng, Ching-Yu, Aung, Tin, Wong, Tien Yin, Ng, Huck Hui, Liu, Jianjun, Wang, Chaolong
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2021
• 主題: Science::Medicine; Whole-genome Sequencing; Asian Populations
• 在線閱讀: https://hdl.handle.net/10356/150428
• 機構: Nanyang Technological University

Underrepresentation of Asian genomes has hindered population and medical genetics research on Asians, leading to population disparities in precision medicine. By whole-genome sequencing of 4,810 Singapore Chinese, Malays, and Indians, we found 98.3 million SNPs and small insertions or deletions, ove...