Automated classification for HEp-2 cells based on linear local distance coding framework

by Xu, Xiang, Lin, Feng, Ng, Carol, Leong, Khai Pang
Published 2015

Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score

by Lim, Ashley JW, Tyniana, C Tera, Lim, Lee Jin, Tan, Justina Wei Lynn, Koh, Ee Tzun, Chong, Samuel S, Khor, Chiea Chuen, Leong, Khai Pang G, Lee, Caroline G
Published 2023

Functional coding haplotypes and machine-learning feature elimination identifies predictors of Methotrexate Response in Rheumatoid Arthritis patients

by Lim, Ashley JW, Lim, Lee Jin, Ooi, Brandon NS, Koh, Ee Tzun, Tan, Justina Wei Lynn, Chong, Samuel S, Khor, Chiea Chuen, Tucker-Kellogg, Lisa, Leong, Khai Pang, Lee, Caroline G
Published 2022

Comparison of mental-physical comorbidity, risk of death and mortality among patients with mental disorders - a retrospective cohort study

by Tan, Xiao Wei, Lee, Eng Sing, Toh, Matthias Paul Han Sim, Lum, Alvin Wai Mun, Seah, Darren Ee Jin, Leong, Khai Pang, Chan, Christopher Yi Wen, Fung, Daniel Shuen Sheng, Tor, Phern Chern
Published 2022

Machine learning using genetic and clinical data identifies a signature that robustly predicts methotrexate response in rheumatoid arthritis

by Lim, Lee Jin, Lim, Ashley JW, BRANDON OOI NICK SERN, Tan, Justina Wei Lynn, Koh, Ee Tzun, Group, Ttsh Rheumatoid Arthritis Study, Chong, Samuel S, Khor, Chiea Chuen, Tucker-Kellogg, Lisa, Lee, Caroline G, Leong, Khai Pang
Published 2022

DUBStepR is a scalable correlation-based feature selection method for accurately clustering single-cell data

by Ranjan, Bobby, Sun, Wenjie, Park, Jinyu, Mishra, Kunal, Schmidt, Florian, Xie, Ronald, Alipour, Fatemeh, Singhal, Vipul, Joanito, Ignasius, Honardoost, Mohammad Amin, Yong, Jacy Mei Yun, Koh, Ee Tzun, Leong, Khai Pang, Rayan, Nirmala Arul, Lim, Michelle Gek Liang, Prabhakar, Shyam
Published 2022

Evaluation of Patients with Vaccine Allergies Prior to mRNA-Based COVID-19 Vaccination

by Lim, Xin Rong, Tan, Justina Wei Lynn, Chan, Grace Yin Lai, Hou, Jinfeng, Xie, Linlin, Goh, Vivian Hui Li, Boon, Joewee, Lee, Samuel Shang Ming, Teo, Claire Min-Li, Tan, Sze Chin, Leong, Khai Pang, Thong, Bernard Yu Hor, Leung, Bernard Pui Lam
Published 2023

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

by Huang, Zhenxing, Wang, Jianhe, Xu, Xiaoli, Wang, Haishan, Qiao, Yuan, Chu, Wern Cui, Xu, Shengli, Chai, Louis, Cottier, Fabien, Pavelka, Norman, Oosting, Marije, Joosten, Leo A. B., Netea, Mihai, Ng, Carol Yee Leng, Leong, Khai Pang, Kundu, Parag, Lam, Kong-Peng, Pettersson, Sven, Wang, Yue
Published 2021

Pseudo-Anaphylactic Reactions to Pfizer BNT162b2 Vaccine: Report of 3 Cases of Anaphylaxis Post Pfizer BNT162b2 Vaccination

by Lim, Xin Rong, Leung, Bernard Pui, Ng, Carol Yee Leng, Tan, Justina Wei Lynn, Chan, Grace Yin Lai, Loh, Chien Mei, Tan, Gwendolyn Li Xuan, Goh, Valerie Hui Hian, Wong, Lok To, Chua, Chong Rui, Tan, Sze Chin, Lee, Samuel Shang Ming, Howe, Hwee Siew, Thong, Bernard Yu Hor, Leong, Khai Pang
Published 2021

Clinical remission of rheumatoid arthritis in a multicenter real-world study in Asia-Pacific region

by Xing Sun, Ru Li, Yueming Cai, Adeeba Al-Herz, Manjari Lahiri, Minhaj Rahim Choudhury, Rudy Hidayat, Bagus Putu Putra Suryana, Yuko Kaneko, Keishi Fujio, Nguyen Van Hung, Sapan Pandya, Leong Khai Pang, Wanruchada Katchamart, Keshav Raj Sigdel, Buddhi Paudyal, Pongthorn Narongroeknawin, Parawee Chevaisrakul, Feng Sun, Yu Lu, Carmen Ho, Swan Sim Yeap, Zhanguo Li
Published 2022

Analysis of clinically relevant variants from ancestrally diverse Asian genomes

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John Campbell, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S., Ngeow, Joanne, Lim, Weng Khong
Published 2023

Large-scale whole-genome sequencing of three diverse Asian populations in Singapore

by Wu, Degang, Dou, Jinzhuang, Chai, Xiaoran, Bellis, Claire, Wilm, Andreas, Shih, Chih Chuan, Soon, Wendy Wei Jia, Bertin, Nicolas, Lin, Clarabelle Bitong, Khor, Chiea Chuen, DeGiorgio, Michael, Cheng, Shanshan, Bao, Li, Karnani, Neerja, Hwang, William Ying Khee, Davila, Sonia, Tan, Patrick, Shabbir, Asim, Moh, Angela, Tan, Eng-King, Foo, Jia Nee, Goh, Liuh Ling, Leong, Khai Pang, Foo, Roger Sik Yin, Lam, Carolyn Su Ping, Richards, Arthur Mark, Cheng, Ching-Yu, Aung, Tin, Wong, Tien Yin, Ng, Huck Hui, Liu, Jianjun, Wang, Chaolong
Published 2021

Analysis of clinically relevant variants from ancestrally diverse Asian genomes.

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, SG10K_Health Consortium, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John C, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S, Ngeow, Joanne, Lim, Weng Khong
Published 2022

A five-safes approach to a secure and scalable genomics data repository

by Shih, Chih Chuan, Chen, Jieqi, Lee, Ai Shan, Bertin, Nicolas, Hebrard, Maxime, Khor, Chiea Chuen, Li, Zheng, Tan, Joanna Juan Hui, Meah, Wee Yang, Peh, Su Qin, Mok, Shi Qi, Sim, Kar Seng, Liu, Jianjun, Wang, Ling, Wong, Eleanor, Li, Jingmei, Aung, Tin, Cheng, Ching-Yu, Heng, Chew-Kiat, Yuan, Jian-Min, Koh, Woon-Puay, Saw, Seang Mei, Friedlander, Yechiel, Sim, Xueling, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Tien Yin, Karnani, Neerja, Leong, Khai Pang, Yeo, Khung Keong, Chambers, John C., Lim, Su Chi, Goh, Rick Siow Mong, Tan, Patrick, Dorajoo, Rajkumar
Published 2023

The Singapore national precision medicine strategy

by Wong, Eleanor, Bertin, Nicolas, Hebrard, Maxime, Tirado-Magallanes, Roberto, Bellis, Claire, Lim, Weng Khong, Chua, Chee Yong, Tong, Philomena Mei Lin, Chua, Raymond, Mak, Kenneth, Lim, Tit Meng, Cheong, Wei Yang, Thien, Kwee Eng, Goh, Khean Teik, Chai, Jin-Fang, Lee, Jimmy, Sung, Joseph Jao Yiu, Wong, Tien Yin, Chin, Calvin Woon Loong, Gluckman, Peter D., Goh, Liuh Ling, Ban, Kenneth Hon Kim, Tan, Tin Wee, Sim, Xueling, Cheng, Ching-Yu, Davila, Sonia, Karnani, Neerja, Leong, Khai Pang, Liu, Jianjun, Prabhakar, Shyam, Maurer-Stroh, Sebastian, Verma, Chandra Shekhar, Krishnaswamy, Pavitra, Goh, Rick Siow Mong, Chia, Irenaeus, Ho, Clarissa, Low, Doreen, Virabhak, Suchin, Yong, Jacklyn, Zheng, Weiling, Seow, Shih Wee, Seck, Yee Kwang, Koh, Mingshi, Chambers, John Campbell, Tai, E. Shyong, Tan, Patrick
Published 2023