Polygenic risk scores for complex diseases: where are we now?

by Loh, Marie, Chambers, John Campbell
Published 2023

Epigenetic disturbances in obesity and diabetes : epidemiological and functional insights

by Loh, Marie, Zhou, Li, Ng, Hong Kiat, Chambers, John Campbell
Published 2020

Contribution of lower physical activity levels to higher risk of insulin resistance and associated metabolic disturbances in South Asians compared to Europeans

by Afaq, Saima, Kooner, Angad S., Loh, Marie, Kooner, Jaspal S., Chambers, John Campbell
Published 2019

Investigating causal relationships between Body Mass Index and risk of atopic dermatitis : a Mendelian randomization analysis

by Yew, Yik Weng, Loh, Marie, Thng, Steven Tien Guan, Chambers, John Campbell
Published 2021

Characteristics and outcomes of community health worker training to improve the prevention and control of cardiometabolic diseases in low and middle-income countries: a systematic...

by Seneviratne, Shilanthi, Desloge, Allissa, Haregu, Tilahun, Kwasnicka, Dominika, Kasturiratne, Anuradhani, Mandla, Anika, Chambers, John Campbell, Oldenburg, Brian
Published 2023

Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing

by Schuster, Stephan C., Beck, Stephan, Kim, Changhoon, Chambers, John Campbell, Loh, Marie, Zhou, Li, Ng, Hong Kiat, Drautz-Moses, Daniela I.
Published 2019

Enhancing care quality and accessibility through digital technology-supported decentralisation of hypertension and diabetes management: a proof-of-concept study in rural Bangladesh

by Xie, Wubin, Paul, Rina Rani, Goon, Ian Y., Anan, Aysha, Rahim, Aminur, Hossain, Md Mokbul, Hersch, Fred, Oldenburg, Brian, Chambers, John Campbell, Mridha, Malay Kanti
Published 2024

The development and validation of a macronutrient and taste preference ranking task in multiethnic Asian population

by Shua, Irving Yu Le, Dewinta, Rahmania Putri, Teo, Pey Sze, Low, Dorrain Yanwen, Bhaskaran, Kalpana, Loh, Win Nie, Lim, Yen Peng, Chambers, John Campbell, Mina, Theresia
Published 2024

Elevated levels of organochlorine pesticides in South Asian immigrants are associated with an increased risk of diabetes

by Elliott, Paul, Kooner, Jaspal, Macherone, Anthony, McMullin, Matthew, Zhang, Luoping, Chambers, John Campbell, Sanchez, Sylvia S., La Merrill, Michele A., Hubbard, Alan E., Smith, Martyn T., Daniels, Sarah I.
Published 2019

Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort

by Yew, Yik Weng, Mina, Theresia, Ng, Hong Kiat, Lam, Benjamin Chih Chiang, Riboli, Elio, Lee, Eng Sing, Lee, Jimmy, Ngeow, Joanne, Elliott, Paul, Thng, Steven Tien Guan, Chambers, John Campbell, Loh, Marie
Published 2023

Network reconstruction for trans acting genetic loci using multi-omics data and prior information

by Hawe, Johann S., Saha, Ashis, Waldenberger, Melanie, Kunze, Sonja, Wahl, Simone, Müller-Nurasyid, Martina, Prokisch, Holger, Grallert, Harald, Herder, Christian, Peters, Annette, Strauch, Konstantin, Theis, Fabian J., Gieger, Christian, Chambers, John Campbell, Battle, Alexis, Heinig, Matthias
Published 2023

Smokeless and combustible tobacco use among 148,944 South Asian adults: a cross-sectional study of South Asia Biobank

by Xie, Wubin, Mridha, Malay Kanti, Gupta, Anaya, Kusuma, Dian, Butt, Awais Muhammad, Hasan, Mehedi, Brage, Soren, Loh, Marie, Khawaja, Khadija Irfan, Pradeepa, Rajendra, Jha, Vinita, Kasturiratne, Anuradhani, Katulanda, Prasad, Anjana, Ranjit Mohan, Chambers, John Campbell
Published 2024

Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome

by Rozario, Pritisha, Pinilla, Miriam, Gorse, Leana, Vind, Anna Constance, Robinson, Kim S., Toh, Gee Ann, Muhammad Jasrie Firdaus, Martínez, José Francisco, Kerk, Swat Kim, Lin, Zhewang, Chambers, John Campbell, Bekker-Jensen, Simon, Meunier, Etienne, Zhong, Franklin
Published 2024

Food environment and diabetes mellitus in South Asia: a geospatial analysis of health outcome data

by Kusuma, Dian, Atanasova, Petya, Pineda, Elisa, Anjana, Ranjit Mohan, De Silva, Laksara, Hanif, Abu Am, Hasan, Mehedi, Hossain, Md. Mokbul, Indrawansa, Susantha, Jayamanne, Deepal, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I., Kumarendran, Balachandran, Mridha, Malay K., Rajakaruna, Vindya, Chambers, John Campbell, Frost, Gary, Sassi, Franco, Miraldo, Marisa
Published 2022

The iHealth-T2D study: a cluster randomised trial for the prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes-a statistical analysis plan

by Muilwijk, Mirthe, Loh, Marie, Mahmood, Sara, Palaniswamy, Saranya, Siddiqui, Samreen, Silva, Wnurinham, Frost, Gary S., Gage, Heather M., Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P., Ahmad, Sajjad, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I., Kooner, Jaspal S., Wickremasinghe, Ananda R., van Valkengoed, Irene G. M., Chambers, John Campbell
Published 2023

Food environments and obesity: a geospatial analysis of the South Asia Biobank, income and sex inequalities

by Atanasova, Petya, Kusuma, Dian, Pineda, Elisa, Anjana, Ranjit Mohan, De Silva, Laksara, Hanif, Abu A. M., Hasan, Mehedi, Hossain, Md Mokbul, Indrawansa, Susantha, Jayamanne, Deepal, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I., Kumarendran, Balachandran, Mrida, Malay K., Rajakaruna, Vindya, Chambers, John Campbell, Frost, Gary, Sassi, Franco, Miraldo, Marisa
Published 2023

DNA methylation and lipid metabolism : an EWAS of 226 metabolic measures

by Gomez-Alonso, Monica del C., Kretschmer, Anja, Wilson, Rory, Pfeiffer, Liliane, Karhunen, Ville, Seppälä, Ilkka, Zhang, Weihua, Mittelstraß, Kirstin, Wahl, Simone, Matias-Garcia, Pamela R., Prokisch, Holger, Horn, Sacha, Meitinger, Thomas, Serrano-Garcia, Luis R., Sebert, Sylvain, Raitakari, Olli, Loh, Marie, Rathmann, Wolfgang, Müller-Nurasyid, Martina, Herder, Christian, Roden, Michael, Hurme, Mikko, Jarvelin, Marjo-Riitta, Ala-Korpela, Mika, Kooner, Jaspal S., Peters, Annette, Lehtimäki, Terho, Chambers, John Campbell, Gieger, Christian, Kettunen, Johannes, Waldenberger, Melanie
Published 2021

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes

by McAllan, Liam, Baranasic, Damir, Villicaña, Sergio, Brown, Scarlett, Zhang, Weihua, Lehne, Benjamin, Adamo, Marco, Jenkinson, Andrew, Elkalaawy, Mohamed, Mohammadi, Borzoueh, Hashemi, Majid, Fernandes, Nadia, Lambie, Nathalie, Williams, Richard, Christiansen, Colette, Yang, Youwen, Zudina, Liudmila, Lagou, Vasiliki, Tan, Sili, Castillo-Fernandez, Juan, King, James W. D., Soong, Richie, Elliott, Paul, Scott, James, Prokopenko, Inga, Cebola, Inês, Loh, Marie, Lenhard, Boris, Batterham, Rachel L., Bell, Jordana T., Chambers, John Campbell, Kooner, Jaspal S., Scott, William R.
Published 2023

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

by Goyal, Shiwali, Tanigawa, Yosuke, Zhang, Weihua, Chai, Jin-Fang, Almeida, Marcio, Sim, Xueling, Lerner, Megan, Chainakul, Juliane, Ramiu, Jonathan Garcia, Seraphin, Chanel, Apple, Blair, Vaughan, April, Muniu, James, Peralta, Juan, Lehman, Donna M., Ralhan, Sarju, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Sidorov, Evgeny, Peyton, Marvin D., Blackett, Piers R., Curran, Joanne E., Tai, E Shyong, van Dam, Rob, Cheng, Ching-Yu, Duggirala, Ravindranath, Blangero, John, Chambers, John Campbell, Sabanayagam, Charumathi, Kooner, Jaspal S., Rivas, Manuel A., Aston, Christopher E., Sanghera, Dharambir K.
Published 2022

Analysis of clinically relevant variants from ancestrally diverse Asian genomes

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John Campbell, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S., Ngeow, Joanne, Lim, Weng Khong
Published 2023