Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

by Prabhakar, Shyam, Jauch, Ralf, Ng, Calista K. L., Li, Noel X., Chee, Sheena., Kolatkar, Prasanna R.
Published 2014

Transposable elements that have recently been mobile in the human genome

by Autio, Matias, I, Bin Amin, Talal, Perrin, Arnaud, Wong, Jen Yi, Foo, Roger S-Y, Prabhakar, Shyam
Published 2022

scConsensus: combining supervised and unsupervised clustering for cell type identification in single-cell RNA sequencing data

by Ranjan, Bobby, Schmidt, Florian, Sun, Wenjie, Park, Jinyu, Honardoost, Mohammad Amin, Tan, Joanna, Arul Rayan, Nirmala, Prabhakar, Shyam
Published 2022

MiR‐135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF‐β/BMP signaling

by Bhinge, Akshay, Poschmann, Jeremie, Namboori, Seema C., Tian, Xianfeng, Loh, Sharon Jia Hui, Traczyk, Anna, Prabhakar, Shyam, Stanton, Lawrence W.
Published 2015

TherMos : estimating protein-DNA binding energies from in vivo binding profiles

by Sun, Wenjie, Hu, Xiaoming, Choo, Siew Hua, Drechsel, Daniela, Guillemot, Franc, Jauch, Ralf, Prabhakar, Shyam, Lim, Michael H. K., Ng, Calista K. L., Castro, Diogo S., Kolatkar, Prasanna R.
Published 2014

ACSL1 is associated with fetal programming of insulin sensitivity and cellular lipid content

by Joseph, Roy, Poschmann, Jeremie, Sukarieh, Rami, Too, Peh Gek, Julien, Sofi G., Xu, Feng, Teh, Ai Ling, Holbrook, Joanna D, Ng, Kai Lyn, Chong, Yap Seng, Gluckman, Peter D., Prabhakar, Shyam, Stünkel, Walter
Published 2015

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis

by Ingham, Philip William, Prabhakar, Shyam, Leow, Melvin K. S., Lee, Yung Seng, Ng, Kai Lyn, Leow, Shi Chi, Poschmann, Jeremie, Too, Peh Gek, Yin, Juan, Joseph, Roy, McFarlane, Craig, Dogra, Shaillay, Shabbir, Asim, Chong, Yap Seng, Gluckman, Peter D., Stünkel, Walter
Published 2018

DUBStepR is a scalable correlation-based feature selection method for accurately clustering single-cell data

by Ranjan, Bobby, Sun, Wenjie, Park, Jinyu, Mishra, Kunal, Schmidt, Florian, Xie, Ronald, Alipour, Fatemeh, Singhal, Vipul, Joanito, Ignasius, Honardoost, Mohammad Amin, Yong, Jacy Mei Yun, Koh, Ee Tzun, Leong, Khai Pang, Rayan, Nirmala Arul, Lim, Michelle Gek Liang, Prabhakar, Shyam
Published 2022

Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease

by Bardile, Costanza Ferrari, Garcia-Miralles, Marta, Caron, Nicholas S., Rayan, Nirmala Arul, Langley, Sarah Raye, Harmston, Nathan, Rondelli, Ana Maria, Teo, Roy Tang Yi, Waltl, Sabine, Anderson, Lisa M., Bae, Han-Gyu, Jung, Sangyong, Williams, Anna, Prabhakar, Shyam, Petretto, Enrico, Hayden, Michael R., Pouladi, Mahmoud A.
Published 2020

Human Nasal Epithelial Cells Sustain Persistent SARS-CoV-2 Infection In Vitro, despite Eliciting a Prolonged Antiviral Response

by Gamage, Akshamal M, Tan, Kai Sen, Chan, Wharton OY, Lew, Zhe Zhang Ryan, Liu, Jing, Tan, Chee Wah, Rajagopalan, Deepa, Lin, Quy Xiao Xuan, Tan, Le Min, Venkatesh, Prasanna Nori, Ong, Yew Kwang, Thong, Mark, Lin, Raymond Tzer Pin, Prabhakar, Shyam, Wang, De Yun, Wang, Lin-Fa
Published 2022

Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity

by Lin, Quy Xiao Xuan, Rajagopalan, Deepa, Gamage, Akshamal M., Tan, Le Min, Venkatesh, Prasanna Nori, Chan, Wharton O. Y., Kumar, Dilip, Agrawal, Ragini, Chen, Yao, Fong, Siew-Wai, Singh, Amit, Sun, Louisa J., Tan, Seow-Yen, Chai, Louis Yi Ann, Somani, Jyoti, Lee, Bernett, Renia, Laurent, Ng, Lisa F. P., Ramanathan, Kollengode, Wang, Lin-Fa, Young, Barnaby, Lye, David, Singhal, Amit, Prabhakar, Shyam
Published 2024

Analysis of clinically relevant variants from ancestrally diverse Asian genomes

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John Campbell, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S., Ngeow, Joanne, Lim, Weng Khong
Published 2023

Analysis of clinically relevant variants from ancestrally diverse Asian genomes.

by Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, SG10K_Health Consortium, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John C, Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S, Ngeow, Joanne, Lim, Weng Khong
Published 2022

The Singapore national precision medicine strategy

by Wong, Eleanor, Bertin, Nicolas, Hebrard, Maxime, Tirado-Magallanes, Roberto, Bellis, Claire, Lim, Weng Khong, Chua, Chee Yong, Tong, Philomena Mei Lin, Chua, Raymond, Mak, Kenneth, Lim, Tit Meng, Cheong, Wei Yang, Thien, Kwee Eng, Goh, Khean Teik, Chai, Jin-Fang, Lee, Jimmy, Sung, Joseph Jao Yiu, Wong, Tien Yin, Chin, Calvin Woon Loong, Gluckman, Peter D., Goh, Liuh Ling, Ban, Kenneth Hon Kim, Tan, Tin Wee, Sim, Xueling, Cheng, Ching-Yu, Davila, Sonia, Karnani, Neerja, Leong, Khai Pang, Liu, Jianjun, Prabhakar, Shyam, Maurer-Stroh, Sebastian, Verma, Chandra Shekhar, Krishnaswamy, Pavitra, Goh, Rick Siow Mong, Chia, Irenaeus, Ho, Clarissa, Low, Doreen, Virabhak, Suchin, Yong, Jacklyn, Zheng, Weiling, Seow, Shih Wee, Seck, Yee Kwang, Koh, Mingshi, Chambers, John Campbell, Tai, E. Shyong, Tan, Patrick
Published 2023